diff --git a/test/E2ETests/DeploymentUtility.cs b/test/E2ETests/DeploymentUtility.cs
index f030c35a1d..80683793d6 100644
--- a/test/E2ETests/DeploymentUtility.cs
+++ b/test/E2ETests/DeploymentUtility.cs
@@ -48,6 +48,8 @@ namespace E2ETests
             string applicationPath = Path.GetFullPath(Path.Combine(Environment.CurrentDirectory, APP_RELATIVE_PATH));
             //Tweak the %PATH% to the point to the right KREFLAVOR
             Environment.SetEnvironmentVariable("PATH", SwitchPathToKreFlavor(kreFlavor));
+            //To avoid the KRE_DEFAULT_LIB of the test process flowing into Helios, set it to empty
+            Environment.SetEnvironmentVariable("KRE_DEFAULT_LIB", string.Empty);
 
             if (hostType == HostType.Helios)
             {
diff --git a/test/E2ETests/SmokeTests.cs b/test/E2ETests/SmokeTests.cs
index 9304b1ec04..b0711d9a22 100644
--- a/test/E2ETests/SmokeTests.cs
+++ b/test/E2ETests/SmokeTests.cs
@@ -18,7 +18,7 @@ namespace E2ETests
         [Theory]
         [InlineData(HostType.Helios, KreFlavor.DesktopClr, "http://localhost:5001/")]
         [InlineData(HostType.SelfHost, KreFlavor.DesktopClr, "http://localhost:5002/")]
-        //[InlineData(HostType.Helios, KreFlavor.CoreClr, "http://localhost:5001/")]
+        [InlineData(HostType.Helios, KreFlavor.CoreClr, "http://localhost:5001/")]
         [InlineData(HostType.SelfHost, KreFlavor.CoreClr, "http://localhost:5002/")]
         public void SmokeTestSuite(HostType hostType, KreFlavor kreFlavor, string applicationBaseUrl)
         {