diff --git a/src/Microsoft.AspNetCore.Blazor.Browser.JS/src/Services/UriHelper.ts b/src/Microsoft.AspNetCore.Blazor.Browser.JS/src/Services/UriHelper.ts
index 734fe80a24..c4e8fcbf1b 100644
--- a/src/Microsoft.AspNetCore.Blazor.Browser.JS/src/Services/UriHelper.ts
+++ b/src/Microsoft.AspNetCore.Blazor.Browser.JS/src/Services/UriHelper.ts
@@ -22,7 +22,7 @@ registerFunction(`${registeredFunctionPrefix}.enableNavigationInterception`, ()
     // We must explicitly check if it has an 'href' attribute, because if it doesn't, the result might be null or an empty string depending on the browser
     const anchorTarget = findClosestAncestor(event.target as Element | null, 'A') as HTMLAnchorElement;
     const hrefAttributeName = 'href';
-    if (anchorTarget && anchorTarget.hasAttribute(hrefAttributeName)) {
+    if (anchorTarget && anchorTarget.hasAttribute(hrefAttributeName) && event.button === 0) {
       const href = anchorTarget.getAttribute(hrefAttributeName)!;
       const absoluteHref = toAbsoluteUri(href);